DNA Nanostructure-Programmed Like-Charge Attraction at the Cell-Membrane Interface
نویسندگان
چکیده
منابع مشابه
Like-charge attraction
As we learned from mean-field theory, like-chared particles repel. However, in the last decade, like-charge polyelectrolyte attraction was observed in the presence of multivalent ions in a variety of biological systems, including DNA, F-actin, microtubules, and filamentous viruses. Considering the fundermental role DNA played in the lifecycle, we find like-charge attraction is not only physical...
متن کاملRole of geometrical shape in like-charge attraction of DNA.
While the phenomenon of like-charge attraction of DNA is clearly observed experimentally and in simulations, mean-field theories fail to predict it. Kornyshev et al. argued that like-charge attraction is due to DNA's helical geometry and hydration forces. Strong-coupling (SC) theory shows that attraction of like-charged rods is possible through ion correlations alone at large coupling parameter...
متن کاملIon multivalence and like-charge polyelectrolyte attraction.
It is known empirically that multivalent ions generate attractions between like-charged polyelectrolytes, with different valence requirements for different systems. How multivalent must an ion be before it can condense a given polyelectrolyte? Using charge-tunable M13 virus rods and a family of artificial homologous "dumbbell" divalent ions of different sizes, we have constructed a multivalent ...
متن کاملLike-Charge Attraction through Hydrodynamic Interaction
We demonstrate that the attractive interaction measured between likecharged colloidal spheres near a wall can be accounted for by a nonequilibrium hydrodynamic effect. We present both analytical results and Brownian dynamics simulations which quantitatively capture the onewall experiments of Larsen and Grier (Nature 385, 230, 1997).
متن کاملLike-charge attraction and hydrodynamic interaction
We demonstrate that the attractive interaction measured between like-charged colloidal spheres near a wall can be accounted for by a nonequilibrium hydrodynamic effect. We present both analytical results and Brownian dynamics simulations which quantitatively capture the one-wall experiments of Larsen and Grier [Nature (London) 385, 230 (1997)], using a single unmeasured parameter.
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ژورنال
عنوان ژورنال: ACS Central Science
سال: 2018
ISSN: 2374-7943,2374-7951
DOI: 10.1021/acscentsci.8b00383